Most of the intervention games (nine out of seventeen) were designed according to specific behavioral change theories, predominantly the social cognitive theory (SCT) and the self-determination theory (SDT), but also the Elaboration Likelihood Model. (4) Conclusions: studies confirmed the potential of serious games for obesity prevention but considering the restrictions encountered, we exhort for novel designs with different theoretical perspectives. Most of the intervention’s games were designed according to specific behavioral change theories, predominantly the social cognitive theory. Half of the studies tested interventions for healthy eating and physical education. (3) Results: a total of 26 studies were identified, representing 17 games. Peer-reviewed journal articles published between 20 were selected for data extraction. Five electronic bibliographic databases-PubMed, ACM Digital Library, Games for Health Journal, and IEEE Xplore were used to conduct a systematic literature search based on fixed inclusion and exclusion criteria. (2) Methods: this systematic review aimed to analyze the effect of serious games in promoting healthy eating behaviors, effectively preventing childhood obesity, and improving physical activity in children. (1) Background: serious games seem to show promising strategies to promote treatment compliance and motivate behavior changes, and some studies have proven to contribute to the literature on serious games.

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